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. 2019 Jan 21;10(2):378–390. doi: 10.1002/jcsm.12377

Figure 6.

Figure 6

Pancreatic ductal adenocarcinoma‐induced systemic and central nervous system inflammation is diminished by blocking MyD88 signalling. Mice were euthanized on Days 11–12 post‐implantation. (A) White blood cell (WBC) and neutrophil and lymphocyte counts. (B) Serum interleukin‐6 levels. (C, D) Liver inflammatory gene expression. (E) Hypothalamic inflammatory gene expression. (F) Cortex inflammatory gene expression. *, P < 0.05; **, P < 0.01; ***, P < 0.001; sham vs. KPC. Two‐way analysis of variance with post hoc Bonferroni‐corrected t‐test. N = 5/group.