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MyD88 signalling contributes to high mortality in PDAC. Sex, age, and body weight‐matched WT and MyD88 KO mice were implanted with 3 × 106 KPC cells through orthotopic route. (A) Survival curves in male and female mice. (B) Initial body weight in male and female mice pre‐tumour implantation. (C) Terminal tumour weight in male and female mice. *, P < 0.05; **, P < 0.01; ***, P < 0.001; WT/KPC vs. MyD88KO/KPC. Comparison of survival curves with Log‐rank (Mantel‐Cox) test. N = 8/group.
