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. Author manuscript; available in PMC: 2020 Mar 10.
Published in final edited form as: J Control Release. 2019 Jan 25;297:3–13. doi: 10.1016/j.jconrel.2019.01.036

Figure 4.

Figure 4.

Histological sections of murine periodontal tissues, with inflammatory cell infiltration denoted with black arrows. (A) Periodontal tissue of uninfected, untreated (control) mice shows normal histological structure without inflammatory cell infiltration. (B) Periodontal tissue of Pg/Sg infected mice demonstrates prominent chronic inflammation through proliferation of connective tissue and heavy infiltration of inflammatory cells. (C) Periodontal tissue of mice treated with 0.7 μM BAR exhibits medium infiltration of inflammatory cells. (D) & (E) Periodontal tissues treated with a higher concentration of free BAR (3.4 μM) or BNPs show normal histological structure with minimal infiltration of inflammatory cells. (H&E, 100x).