Table 2.
Post-treatment Changes in Size and Avidity of Tumor on PET/CT
| Residual lymphoma | No residual lymphoma | P value | |
|---|---|---|---|
| Total patients | 18 | 16 | 0.731 |
| Initial diagnostic procedure | |||
| Axillary lymph node biopsy | 1 | 3 | 0.317 |
| Cervical lymph node biopsy | 6 | 2 | 0.157 |
| Core needle mediastinal | 5 | 7 | 0.564 |
| procedure | |||
| Minimally invasive surgery | 6 | 4 | 0.480 |
| Imaging characteristics | |||
| Mean pretreatment SUVmax | 19 (12.2–27.2) | 312.9 (8.2–17.6) | 0.155 |
| Mean posttreatment | 9 (4.4–13.6) | 5 (3.0–6.7) | 0.136 |
| SUVmax | |||
| Mean pretreatment CT size | 9 (6.3–11.7) | 8 (5.9–10.9) | 0.738 |
| Mean posttreatment CT size | 5 (3.1 – 6.3) | 4 (2.5–4.7) | 0.282 |
| Imaging changes | |||
| Mean reduction in SUVmax | 61% (45.5–75.5) | 689% (51.9–85.7) | 0.478 |
| Mean reduction in CT size | 40% (20.9–58.3) | 51.% (30.9–71.7) | 0.418 |
| Method of tissue sample | |||
| Minimally invasive | 11 | 12 | 0.835 |
| Open procedure | 5 | 4 | 0.740 |
| Core needle biopsy | 2 | 0 | 0.158 |
Note. CT size defined as length (cm) of longest tumor axis. Mean reduction in SUVmax calculated as (SUVmaxinitial – SUVmaxfinal)/SUVmaxinitial. Mean reduction in CT size calculated as ((CTinitial - CTfinal)/CTinitial). Open procedures include thoracotomy, sternotomy, transcervical, transbronchial. Minimally invasive procedures include mediastinoscopy, VATS, robotic. Chi square test p value calculated for categorical variables and two sample t test p value calculated to compare means.