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. Author manuscript; available in PMC: 2019 Apr 15.
Published in final edited form as: Cell Rep. 2018 Dec 11;25(11):2955–2962.e3. doi: 10.1016/j.celrep.2018.11.060

Figure 3. Linker Interactions.

Figure 3.

The inter-domain linker connecting HD1 and HD2 of DUX4 is shown in green. Trp85 docks into a hydrophobic pocket on the HD1 surface. Other residues from the linker also make protein or DNA contacts to coordinate positioning of the two homeodomains. Solid and transparent surfaces are shown for HD1 and HD2, respectively.