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. 2019 Mar 28;41:20–28. doi: 10.1016/j.amsu.2019.03.009

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This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 4 — Motor Function Assessment. A. Walking track analysis: progression of walking track (foot prints) of normal (naïve), and nerve transected/repaired animals in vehicle (Control) and mesenchymal stem cell (MSC) treated (Treatment) groups in individual nerve repair (INR) and sciatic nerve repair (SNR) models up to 18 weeks post nerve repair are shown. In INR with MSC treatment footprints improved significantly compared to the vehicle control group; INR footprints were better than the SNR footprints. B, Sciatic Function Index: a measure of the motor function calculated from footprints (see materials and methods) was significantly improved (P < 0.05) in INR with MSC treatment compared to vehicle-treated control. Also, SFI was markedly improved in SNR with MSC treatment compared to vehicle-treated control. Interestingly, SFI (footprints) in INR was significantly better than SNR. Solid square = INR MSC treatment (n = 10); Empty square = INR Vehicle control (n = 12); Solid circle = SNR MSC treatment N = 9); and Empty circle = SNR Vehicle control (n = 12).