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. 2019 Mar 28;41:20–28. doi: 10.1016/j.amsu.2019.03.009

Fig. 6.

Fig. 6

Histomorphometry of the tibial nerve in individual nerve repair model. Toluidine Blue stained nerve cross-section images (400x) were processed using ImageJ software (NIH, Bethesda, MD) to determine axonal size and myelination. A. Axon diameter/size (area): significant decrease in axonal area in the right repaired nerve (RN) compared to contralateral naïve left nerve (LN) in both control (C) (P < 0.01) and MSC (P < 0.001) treated groups were observed. B, Axon myelination (g ratio): in vehicle-treated control group, myelination (g ratio) was significantly (P < 0.01) reduced in the right repaired nerve (RN-C) compared to the contralateral naïve left nerve (LN-C). In MSC treated group there was no significant difference (P > 0.05) in myelination (g ratio) between the naïve left nerve (LN-MSC) and repaired right nerve (RN-MSC). ns, non-significant, MSC, Mesenchymal Stem Cells; *P < 0.05, **P < 0.01, ***P < 0.001.