Table 2.

Reasons for exit from Auto Mode into OL Manual Mode during 3-month trial phase

	Period	Mean ± SD	P value*
Percentage time in HCL	Days 1–7	87.0 ± 10.8
	Days 22–28	80.2 ± 15.5	0.019
	Days 50–56	76.0 ± 14.2	0.25
	Days 78–84	71.8 ± 23.3	0.26
Mean number of events removing participant from HCL
Total (events/week)	Days 1–7	5.3 ± 2.7
	Days 22–28	5.4 ± 2.5
	Days 50–56	5.8 ± 1.9
	Days 78–84	5.8 ± 2.6
System initiated (events/week)	Days 1–7	5.0 ± 2.9
	Days 22–28	5.2 ± 2.6
	Days 50–56	5.5 ± 2.1
	Days 78–84	5.6 ± 2.8
User initiated (events/week)	Days 1–7	0.3 ± 0.7
	Days 22–28	0.2 ± 0.6
	Days 50–56	0.3 ± 0.6
	Days 78–84	0.2 ± 0.5
Percentage of events removing participant from HCL
Safe Basal time-outs	Days 1–7	64.0 ± 23.5
	Days 22–28	76.9 ± 21.3
	Days 50–56	69.8 ± 25.7
	Days 78–84	65.8 ± 28.5
Hyperglycemia and other alerts	Days 1–7	28.3 ± 23.4
	Days 22–28	19.1 ± 18.5
	Days 50–56	23.3 ± 20.1
	Days 78–84	27.2 ± 25.0
User initiated	Days 1–7	7.7 ± 17.8
	Days 22–28	4.0 ± 13.1
	Days 50–56	6.9 ± 15.2
	Days 78–84	7.0 ± 20.3

*Comparison of change from previous period.