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. 2019 Apr 15;38:161. doi: 10.1186/s13046-019-1150-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — LINC01354 promoted proliferation and migration of CRC in vitro. a-b CCK8 and EdU assays were applied to examine cell proliferation ability in si-LINC01354#1/2 transfected LoVo cells and pcDNA3.1/LINC01354 transfected HCT116 cells. c The apoptosis rate in si-LINC01354#1/2 transfected LoVo cells and pcDNA3.1/LINC01354 transfected HCT116 cells was assessed by flow cytometry. d Transwell assays revealed the cell motility in LoVo cells transfected with si-LINC01354#1/2 and HCT116 cells transfected with pcDNA3.1/LINC01354. e-f Western blot and immunofluorescence were utilized to detect EMT associated proteins expression of E-cadherin and Vimentin in the two kinds of CRC cells. Results were exhibited as the mean ± SD on the basis of 3 independent experiments, ^**p < 0.01, ^***p < 0.001