Table 1.

Comparison of the characteristics of interaction between three different cyclins and viral CDK ortholog pUL97

ND means not determined.

Interaction characteristics	Cyclin B1	Cyclin H	Cyclin T1
Strong detectability of interaction by CoIP and MS/MS methods	+	+	±
Interaction dependent on the activity of pUL97	+	−	−
Interaction dependent on HCMV replication	−	+	−
Self-interaction/dimerization of pUL97 supported by cyclins	−	+	+
Intranuclear colocalization	+	+	+
Cytoplasmic cyclin relocalization during HCMV replication	+	−	−
Phosphorylated by pUL97 in vitro	+	−	ND