Table 1.
Patient Characteristics (n = 16 unless stated otherwise).
| Median (IQR) age (years) | 75.3 (67.9–77.8) |
|---|---|
| Sex | |
| Male | 11 (68.7%) |
| Female |
5 (31.3%) |
| ECOG performance status | |
| 0 | 4 (25.0%) |
| 1 | 7 (43.7%) |
| 2 | 2 (12.5%) |
| 3 | 2 (12.5%) |
| Missing |
1 |
| Diagnosis | |
| MDS (RAEB2) | 2 (12.5%) |
| AML transformed from MDS | 5 (31.3%) |
| Other secondary AML | 1 (6.3%) |
| Primary AML | 7 (43.8%) |
| Missing |
1 |
| Median (IQR) time from original diagnosis to trial entry (weeks) | 13.3 (3.6–75.0) |
| Missing |
1 |
| Disease status | |
| Previously untreated | 8 (50.0%) |
| Relapsed | 5 (31.3%) |
| Refractory | 2 (12.5%) |
| Missing |
1 |
| Transfusion dependent (TD) patients | |
| Red blood cell | 9 (56.3%) |
| Platelet | 4 (25.0%) |
| Missing |
1 |
| Haemoglobin in patients that are not red blood cell TD | (n = 6) |
| Median (IQR) Haemoglobin (g/dL) |
10.4 (9.4–12.0) |
| Platelets in patients that are not platelet TD | (n = 11) |
| >100 × 109/L | 4 (36.4%) |
| 20–100 × 109/L | 5 (45.4%) |
| <20 × 109/L |
2 (18.2%) |
| Median counts (IQR) | |
| White cell count (x109/L) | 2.2 (1.4–7.0) |
| Missing |
1 |
| Neutrophils (x109/L) | |
| ≥1 × 109/L | 4 (25.0%) |
| <1 × 109/L | 10 (62.5%) |
| Not known | 1 (6.3%) |
| Missing | 1 |