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. 2016 Dec 15;2016(12):CD001904. doi: 10.1002/14651858.CD001904.pub3

Table 2.

Number of participants contributing to each analysis

Trial Number randomised Time to withdrawal of
allocated treatment
Time to 12‐month
remission
Time to six‐month
remission
Time to first seizure
CBZ PB Total CBZ PB Total CBZ PB Total CBZ PB Total CBZ PB Total
Banu 2007¹ 54 54 108 Information not available Information not available Information not available 54 54 108
de Silva 1996² 54 10 64 53 10 63 54 10 64 54 10 64 54 10 64
Heller 1995³ 61 58 119 60 55 115 61 58 119 61 58 119 61 58 119
Mattson 1985 155 155 310 154 155 309 154 155 309 154 155 309 151 151 302
Ogunrin 2005 19 18 37 Information not available Information not available Information not available 19 18 37
Placencia 1993 95 97 192 94 95 189 95 96 191 95 96 191 95 97 192
Total 438 392 830 361 315 676 364 319 683 364 319 683 434 388 822

CBZ: carbamazepine PB: phenobarbitone ¹The date of withdrawal of allocated treatment was not recorded in all cases for Banu 2007, so we could not calculate 'time to withdrawal of allocated treatment'. The date of first seizure after randomisation was recorded, but all dates of subsequent seizures were not recorded; therefore, we could calculate 'time to first seizure', but we could not calculate 'time to six‐month remission' and 'time to 12‐month remission'. ²We received IPD for 70 participants recruited in de Silva 1996; the randomised drug was not recorded in six participants. Reasons for treatment withdrawal were not available for one participant randomised to CBZ; we did not include this participant in the analysis of time to treatment withdrawal. ³Reasons for treatment withdrawal were not available for four participants (one randomised to CBZ and three to PB) in Heller 1995; we did not include these participants in the analysis of time to treatment withdrawal. ⁴No follow‐up data after randomisation were available for one participant randomised to CBZ in Mattson 1985. Dates of seizure recurrence were not available for seven participants (three randomised to CBZ and four to PB); we did not include these participants in the analysis of time to first seizure. ⁵The study duration of Ogunrin 2005 was 12 weeks; therefore, six‐ and 12‐month remission of seizures could not be achieved, so we could not calculate these outcomes. All randomised participants completed the study without withdrawing from treatment, so we could not analyse the time to treatment withdrawal. ⁶Reasons for treatment withdrawal were not available for three participants (one randomised to CBZ and two randomised to PB) in Placencia 1993. We did not include these participants in the analysis of time to treatment withdrawal. Seizure data after occurrence of first seizure were not available for one participant randomised to PB, so we did not include this participant in the analyses of time to six‐month and time to 12‐month remission.