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. 2016 Dec 15;2016(12):CD001904. doi: 10.1002/14651858.CD001904.pub3
Methods Six‐month, systematic, simple randomised trial of children referred to a child neurology clinic (the author was from Guilan University of Medical Sciences, Iran, so it was likely that the study was also conducted there)
2‐arm trial: CBZ and PB
Participants Children aged 2 to 12 years with partial seizures with secondary generalisation
Number randomised: CBZ = 36, PB = 35
36 male children (53%)
100% partial seizures,
the per cent newly diagnosed was not stated
Age range: 2 to 12 years
Study duration: 6 months
Mean follow‐up: not stated
Interventions Monotherapy with PB or CBZ. Doses started or achieved not stated
Outcomes
  • Proportion seizure‐free

  • Response rate and rate of side‐effects

  • Seizure frequency and seizure duration

Notes The trial was reported in abstract form only with very limited information. Outcomes chosen for this review were not reported; IPD were not available.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk The trial was described as a 'systematic simple randomised study'; no further information was provided.
Allocation concealment (selection bias) Unclear risk No information was provided.
Blinding of participants and personnel (performance bias) All outcomes Unclear risk No information was provided on blinding.
Blinding of outcome assessment (detection bias) All outcomes Unclear risk No information was provided on blinding.
Incomplete outcome data (attrition bias) All outcomes Unclear risk No attrition rates were reported; it was unclear if all participants were analysed.
Selective reporting (reporting bias) Unclear risk There was no protocol available; the study was available in abstract format only. Outcomes for this review were not available.
Other bias Low risk We detected no other bias.