Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
While most ABBA prenyltransferases contain a hydrophobic active site that precludes solvent, the structure of PagF reveals a solvent exposed cavity. Binding of the peptide substrate is necessary to form a solvent excluded cavity where productive prenyl transfer can occur.
