1.10. Analysis.

Comparison 1 RISPERIDONE vs PLACEBO, Outcome 10 Adverse effects: 1c. extrapyramidal ‐ skewed data (various scales) ‐ short term (up to 12 weeks).

Adverse effects: 1c. extrapyramidal ‐ skewed data (various scales) ‐ short term (up to 12 weeks)
Study	Intervention	Mean	SD	N
average change score of AIMS
Potkin 2006	Risperidone	0.3	2.47	153
Potkin 2006	Placebo	‐0.1	2.56	73
average change score of CGI severity dyskinesia
Chouinard 1992	Risperidone	0.3	3.3	22
Chouinard 1992	Placebo	3.5	5.3	22
average change score of CGI severity parkinsonism
Chouinard 1992	Risperidone	0.9	1.5	22
Chouinard 1992	Placebo	0.4	1.3	22
average change score of ESRS
Marder 1994a	Risperidone	2.9	5.7	63
Marder 1994a	Placebo	2.4	5.8	65
average change score of ESRS ‐ akathisia
Marder 1994a	Risperidone	0.6	1.1	63
Marder 1994a	Placebo	0.6	1.6	65
average change score of ESRS ‐ dystonia
Chouinard 1992	Risperidone	0.3	0.8	22
Chouinard 1992	Placebo	1.0	2.3	22
Marder 1994a	Risperidone	1.3	1.3	63
Marder 1994a	Placebo	1.6	1.5	64
Pai 2002	Risperidone	2.1	1.7	22
Pai 2002	Placebo	2.8	1.8	20
average change score of ESRS ‐ dyskinesia
Chouinard 1992	Risperidone	2.6	4.5	22
Chouinard 1992	Placebo	5.7	7.2	SD
Marder 1994a	Risperidone	0.6	1.1	63
Marder 1994a	Placebo	0.5	1.1	65
average change score of ESRS ‐ parkinsonism
Chouinard 1992	Risperidone	2.1	7.5	22
Chouinard 1992	Placebo	2.3	8.7	22
Marder 1994a	Risperidone	0.6	1.1	63
Marder 1994a	Placebo	0.5	1.1	65
Pai 2002	Risperidone	2.1	1.3	22
Pai 2002	Placebo	2.5	1.5	20