Date	Event	Description
13 September 2016	New citation required but conclusions have not changed	Results of update searching added to review. Five new trials added to included studies table. Data from these new trials did not change overall results or conclusions of review.
19 October 2015	New search has been performed	Update search run and 25 references assessed, 2 new studies included.
15 October 2013	Amended	Update search carried out 2013, 69 references assessed, 3 new studies included.
15 March 2013	Feedback has been incorporated	Comments reported in Hutton 2012 regarding including trials with high attrition addressed, sensitivity analysis completed and added to feedback section. Overall results and conclusion of review are unaffected.