TABLE 4.

Key signaling pathways identified being regulated by PMSC exosome miRNAs

Pathway	No. of genes	P
ErbB signaling pathway	59	2.18E−07
Neurotrophin signaling pathway	77	2.70E−07
Focal adhesion	111	2.29E−06
TGF-β signaling pathway	55	2.75E−06
Regulation of actin cytoskeleton	101	6.87E−06
Adherens junction	45	4.86E−05
Axon guidance	67	1.37E−04
Wnt signaling pathway	78	2.73E−04
T cell receptor signaling pathway	56	4.76E−04
mTOR signaling pathway	30	5.47E−04
Jak-STAT signaling pathway	54	2.53E−03
MAPK signaling pathway	124	5.91E−03
Apoptosis	45	7.41E−03
Notch signaling pathway	26	3.75E−02

Jak-STAT, Janus kinase/signal transducer and activator of transcription; mTOR, mammalian target of rapamycin.