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. 2019 Feb 25;33(5):6632–6642. doi: 10.1096/fj.201802373R

TABLE 4.

The rs7940681 SNP associates with an increased risk of IBS

SNP A1 A2 A1 frequency Regression coefficient P IBS definition Case (n) Ctrl (n)
rs7940681 A G 0.506 1.09 0.039 Questionnaire based (Rome IIIa) 1335 9768
rs7940681 A G 0.54 1.03 0.097 Self-reported doctor’s diagnosis 9576 336,499
rs7940681 A G 0.5362 1.03 0.025 Meta-analysis 10,911 34,626

A1, allele 1; A2, allele 2.

a

Rome III criteria for diagnosis of IBS (64).