Perche 2009.

Methods	Double‐blind randomised controlled trial (setting unclear). Recruitment period not stated, at Urquinana Central Hospital, Maracaibo, Zuilia State, Venezuela.
Participants	Women scheduled for admission for cervical ripening and labour induction. Inclusion criteria: included all of the following: singleton fetus, term pregnancies, modified Bishop score < 6, and not in labour. Exclusion criteria: Bishop score > 7, ruptured membranes, chorioamnionitis, bleeding.
Interventions	60 were randomised. 30 were prescribed 40 mg ISMN tablets and 30 received 50 mcg vaginal misoprostol. These medications were repeated every 4 hours for 24 hours. no further details of subsequent treatments were given.
Outcomes	Oxytocin augmentation, Apgar score < 7 at 5 minutes, maternal side effects.
Notes	Original trial report in Spanish and translated prior to extraction. The authors are grateful to Luciana Figuera for her translation.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Random number tables.
Allocation concealment (selection bias)	Low risk	Sealed envelopes.
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Limited reporting unable to make judgement.
Selective reporting (reporting bias)	Unclear risk	Limited reporting unable to make judgement.
Other bias	Unclear risk	Limited reporting unable to make judgement.
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Limited reporting unable to make judgement.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Limited reporting unable to make judgement.