Sharma 2005.

Methods	'Randomised' Inpatient setting. Recruitment between November 2001 and November 2003, Deptartment of Obstetrics and Gynecology, at the All India Institute of Medical Sciences, New Delhi.
Participants	Women scheduled for admission for cervical ripening and labour induction. Inclusion criteria: included all of the following: nulliparity, singleton fetus, modified Bishop score < 6. Exclusion criteria: previous caesarean section and ruptured membranes.
Interventions	65 were randomised into 3 groups. 21 were prescribed 500 mcg GTN (misoprostol) tablets, 21 received 0.5 mg intracervical PGE2 and 23 received 50 mcg of vaginal misoprostol. Women were reassessed at 6 hours and if possible amniotomy was performed. If Bishop score < 6 then further dose of same drug was given.
Outcomes	Maternal: uterine hyperstimulation with and without FHR changes, caesarean section, cervix unfavourable at 12 to 24 hours, oxytocin augmentation, instrumental vaginal delivery and maternal side effects (headache). Neonatal: perinatal death, serious neonatal morbidity or death.
Notes	2 patients (1 from GTN and 1 from misoprostol group excluded due to being delivered by caesarean section after first dose of medication. Not clear if included in final data on caesarean section.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	"Randomised."
Allocation concealment (selection bias)	Unclear risk	No details given.
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	May be concern over 2 post randomisation exclusions.
Selective reporting (reporting bias)	Low risk	No evidence to the contrary.
Other bias	Unclear risk	No evidence to the contrary.
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Not stated.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not stated.