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. 2016 Dec 15;2016(12):CD002830. doi: 10.1002/14651858.CD002830.pub3

Comparison 3. Droperidol versus midazolam.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Tranquillisation or asleep: 1. tranquillised/asleep 1   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
1.1 At 5 minutes 1 153 Risk Ratio (M‐H, Fixed, 95% CI) 0.37 [0.21, 0.64]
1.2 At 10 minutes 1 153 Risk Ratio (M‐H, Fixed, 95% CI) 0.96 [0.72, 1.28]
2 Tranquillisation or asleep: 2 time to tranquillisation/sleep     Other data No numeric data
3 Global state: use of additional medication 1 153 Risk Ratio (M‐H, Fixed, 95% CI) 0.54 [0.24, 1.20]
3.1 By 60 minutes 1 153 Risk Ratio (M‐H, Fixed, 95% CI) 0.54 [0.24, 1.20]
4 Adverse effects 1   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
4.1 Cardiovascular ‐ arrhythmia (bradycardia) 1 153 Risk Ratio (M‐H, Fixed, 95% CI) 2.81 [0.12, 67.98]
4.2 Cardiovascular ‐ hypotension 1 153 Risk Ratio (M‐H, Fixed, 95% CI) 0.70 [0.16, 3.03]
4.3 Central nervous system ‐ dystonic reaction 1 153 Risk Ratio (M‐H, Fixed, 95% CI) 6.56 [0.34, 124.93]
4.4 Central nervous system ‐ seizure 1 153 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
4.5 Gastric ‐ aspiration 1 153 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
4.6 Gastric ‐ vomiting 1 153 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
4.7 Respiratory ‐ airway management 1 153 Risk Ratio (M‐H, Fixed, 95% CI) 0.13 [0.01, 2.55]
4.8 Respiratory ‐ assistance with ventilation 1 153 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
4.9 Respiratory ‐ hypoxia 1 153 Risk Ratio (M‐H, Fixed, 95% CI) 0.70 [0.16, 3.03]