Comparison 4. Droperidol versus olanzapine.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Tranquillisation or asleep: 1. tranquillised/asleep	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
1.1 At 5 minutes	1	221	Risk Ratio (M‐H, Fixed, 95% CI)	1.00 [0.70, 1.42]
1.2 At 10 minutes	1	221	Risk Ratio (M‐H, Fixed, 95% CI)	0.97 [0.81, 1.17]
1.3 At 30 minutes	1	221	Risk Ratio (M‐H, Fixed, 95% CI)	1.02 [0.94, 1.11]
1.4 At 60 minutes	1	221	Risk Ratio (M‐H, Fixed, 95% CI)	0.99 [0.93, 1.05]
2 Tranquillisation or asleep: 2. difficulty in achieving tranquillisation/sleep	1	221	Risk Ratio (M‐H, Fixed, 95% CI)	0.65 [0.11, 3.81]
3 Tranquillisation or asleep: 3. time to tranquillisation/sleep (minutes)	1	221	Mean Difference (IV, Fixed, 95% CI)	7.30 [‐11.74, 26.34]
4 Global state: use of additional medication	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
4.1 'To reach initial adequate sedation"	1	221	Risk Ratio (M‐H, Fixed, 95% CI)	0.68 [0.36, 1.28]
4.2 By 60 minutes (midazolam, droperidol, olanzapine, haloperidol)	1	221	Risk Ratio (M‐H, Fixed, 95% CI)	1.01 [0.63, 1.64]
4.3 From 60 minutes after initial adequate sedation until emergency department discharge (various psychotropic drugs)	1	221	Risk Ratio (M‐H, Fixed, 95% CI)	0.56 [0.36, 0.87]
5 Adverse effects	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
5.1 Cardiovascular ‐ arrhythmia	1	221	Risk Ratio (M‐H, Fixed, 95% CI)	0.32 [0.01, 7.88]
5.2 Cardiovascular ‐ hypotension	1	221	Risk Ratio (M‐H, Fixed, 95% CI)	1.30 [0.30, 5.66]
5.3 Central nervous system ‐ decreased Glasgow Coma Score of 6	1	221	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
5.4 Respiratory ‐ airway obstruction	1	221	Risk Ratio (M‐H, Fixed, 95% CI)	0.97 [0.20, 4.72]
5.5 Respiratory ‐ oxygen desaturation	1	221	Risk Ratio (M‐H, Fixed, 95% CI)	1.75 [0.61, 5.06]
6 Service use: 1. person able to be discharged home	1	221	Risk Ratio (M‐H, Fixed, 95% CI)	1.06 [0.83, 1.34]
7 Service use: 2. emergency department length of stay			Other data	No numeric data