Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy

. 2016 Dec 22;2016(12):CD010378. doi: 10.1002/14651858.CD010378.pub3

Study	Reason for exclusion
Cerqueira 1999	The report involved 34 pregnant women with SCD in a randomised control study published as a conference abstract in 1999 and the full publication of the completed study cannot be located. Trial authors' conclusion in the abstract is suggestive of an incomplete study ("These are still preliminary data and the small number of patients do not allow us to reach a definitive conclusion"). All attempts to contact trial authors for full publication of completed study were unsuccessful.
Koshy 1991	This paper compared the findings of 2 studies on pregnant women with SCD: 1. Koshy 1988 (RCT comparing prophylactic versus selective transfusion for women with HbSS); 2. an observational study on pregnancy outcomes of women with HbSS, SC and Sβ‐Thalassaemia delivering at the same centre over a specified period; with 3. findings in women without medical complications or haemoglobinopathy who delivered the same institution.

Study

Reason for exclusion

Cerqueira 1999

The report involved 34 pregnant women with SCD in a randomised control study published as a conference abstract in 1999 and the full publication of the completed study cannot be located. Trial authors' conclusion in the abstract is suggestive of an incomplete study ("These are still preliminary data and the small number of patients do not allow us to reach a definitive conclusion"). All attempts to contact trial authors for full publication of completed study were unsuccessful.

Koshy 1991

This paper compared the findings of 2 studies on pregnant women with SCD:
1. Koshy 1988 (RCT comparing prophylactic versus selective transfusion for women with HbSS);
2. an observational study on pregnancy outcomes of women with HbSS, SC and Sβ‐Thalassaemia delivering at the same centre over a specified period; with
3. findings in women without medical complications or haemoglobinopathy who delivered the same institution.

RCT: randomised controlled trial  SCD: sickle‐cell disease