Summary of results: 50% pain relief over 4 to 6 hours | |||||||
Dose (mg) | Pain model | Studies | Participants | Celecoxib % | Placebo % | Relative benefit (RB) (95% CI) | NNT (95% CI) 50% |
200 mg | Dental + orthopaedic | 4 | 705 | 35 | 11 | 3.5 (2.4 to 5.1) | 4.2 (3.4 to 5.6) |
200 mg | Dental | 3 | 423 | 34 | 1.4 | 16 (5.1 to 49) | 3.2 (2.7 to 3.9) |
400 mg | Dental | 5 | 722 | 43 | 4.7 | 10 (5.7 to 18) | 2.6 (2.3 to 3.0) |