IND2‐08‐03.

Methods	Randomised, double‐blind, single‐dose, parallel‐group, duration 8 h Medication given when pain ≥ moderate
Participants	Surgical removal of ≥ 2 impacted third molars M and F, age 18 to 50 years N = 203
Interventions	Celecoxib 400 mg, n = 51 Indomethacin 20 mg, n = 50 Indomethacin 40 mg, n = 51 Placebo, n = 51
Outcomes	PI: std 4‐point scale PR: std 5‐point scale Number of participants reporting any adverse event and serious adverse events Number of participants withdrawing due to adverse event
Notes	Clinical trial summary Oxford Quality Score: R1, DB1, W1
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not described
Allocation concealment (selection bias)	Unclear risk	Not described
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Not described
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Unclear how data from withdrawals were handled
Size	Unclear risk	Small treatment group size (50 to 51 participants)