Comparison 3. Anti‐vascular endothelial growth factor (anti‐VEGF) versus sham treatment.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Change in visual acuity at 6 months	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
2 Gain 3+ lines of visual acuity at 6 months	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
3 Central macular thickness at 6 months	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
4 Quality of life at 6 months	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
5 Change in visual acuity at 1 year	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
6 Gain 3+ lines of visual acuity at 1 year	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
7 Choroidal neovascularisation angiographic closure	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
8 Central macular thickness at 1 year	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected