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. 2017 Feb 17;2017(2):CD003225. doi: 10.1002/14651858.CD003225.pub3
Methods D: crossover C: unclear B: double WD: 6/18 J: 1‐1‐1 DU: 1m/2x3m (2w)/‐
Participants N: 18/12 D: all migraine without aura C: Ad Hoc F: 89% A: 18‐49 years DU: 3‐38 years S: probably neurological university outpatient clinic in Italy
Interventions P: 1.8 mg/kg C: Acetylsalicylic acid 13.5 mg/kg
Outcomes R: 9/12 vs. 9/12 (at least 50% index reduction) F: not reported AU: not reported HI: 65% reduction in both groups AEs: 6/12 vs. 6/12 Dropouts‐AEs: 2/18 vs. 3/18 V: 0
Notes Small trial with relatively high dropout rate
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk B ‐ Unclear