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. 2017 Feb 17;2017(2):CD003225. doi: 10.1002/14651858.CD003225.pub3
Methods D: crossover C: unclear B: double WD: 20/56 J: 0‐1‐0 DU: ‐/2x3m (1m)/‐
Participants N: 56/36 D: 12 migraine with, 44 without aura C: unclear F: 66% A: 18‐56 years DU: 1‐33 years S: probably neurology clinic in Glasgow
Interventions P: 120 mg C: Methysergide 3 mg
Outcomes R: 19/36 vs. 13/36 F: frequency lower with propranolol AU: not reported HI: not reported AEs: 12/36 vs. 16/36 Dropouts‐AEs: 0/56 vs. 3/56 V: (+)
Notes High dropout rate
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk B ‐ Unclear