Borgesen 1974

Methods	D: crossover C: unclear B: double WD: 15/45 J: 1‐1‐0 DU: 4w/2x3m/‐
Participants	N: 45/30 D: 15 migraine with, 15 without aura C: Ad Hoc F: 83% A: 18‐59 years DU: 1‐50 years S: neurology department in Denmark
Interventions	P: 120 mg C: Placebo
Outcomes	R: 14/30 vs. 9/30 F: 1.03 (sd 1.02) vs. 1.33 (1.15) attacks per week AU: similar in both groups HI: not reported AEs: not reported Dropouts‐AEs: 0/45 vs. 2/45 V: +
Notes	High dropout rate Responder rates and attack frequency calculated from single patient data presented in the publication
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Unclear risk	B ‐ Unclear