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. 2017 Feb 17;2017(2):CD003225. doi: 10.1002/14651858.CD003225.pub3
Methods D: parallel (with optional crossover) C: unclear B: double WD: 48/148 J: 1‐1‐0 DU: 2m/4w/optional crossover for 6‐12 m
Participants N: 148/100 D: migraine C: Ad Hoc F: not reported A: not reported DU: not reported S: unclear, USA
Interventions P: 80‐160 mg C: Placebo
Outcomes R: not reported F: not reported AU: not reported HI: not reported AEs: not reported Dropouts‐AEs: not reported V: not interpretable
Notes Trial meets the inclusion criteria, but primarily investigates long‐term treatment with propranolol and includes only a 4‐week RCT, whose results, however, are not presented in detail
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk B ‐ Unclear