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. 2017 Feb 17;2017(2):CD003225. doi: 10.1002/14651858.CD003225.pub3
Methods D: crossover C: unclear B: double WD: unclear J: 1‐1‐0 DU: 2w/2x1m (2w)/‐
Participants N: 12/12 (numbers not fully clear) D: migraine with aura C: World Federation of Neurology Research Group F: 67% A: 30‐49 years DU: unclear S: unclear, Denmark
Interventions P: 80 mg C: Metoprolol 100 mg
Outcomes R: not reported F: 2.4 (sem 0.3) vs. 3.1 (0.6) AU: not reported HI: not reported AEs: 0 vs. 0 Dropouts‐AEs: not reported V: uninterpretable
Notes Small study focusing on laboratory parameters
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk B ‐ Unclear