Micieli 2001

Methods	D: crossover C: unclear B: double WD: 10/40 J: 1‐1‐1 DU: 1m/2x3m (1m)/3m
Participants	N: 40/30 D: migraine without aura C: IHS F: 75% A: 35 (sd 10) years DU: 18 years S: unclear, Italy
Interventions	P: 80 mg C: Alpha‐dihydroergocryptine 20 mg
Outcomes	R: not reported F: reduction from 5.2 (sd 1.4) to 1.3 (1.2) vs. 5.4 (1.3) to 1.3 (1.2) (1st period; no pooled data) AU: reduction from 8.5 (sd 4.2) to 2.2 (2.1) vs. 7.7 (3.0) to 2.0 (2.1; analgesic doses) HI: not reported AEs: not reported Dropouts‐AEs: 5/40 vs. 4/40 V: 0
Notes	High dropout rate Significant baseline differences in duration of attacks and psychological profile No significant carryover effect
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Unclear risk	B ‐ Unclear