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. 2017 Feb 17;2017(2):CD003225. doi: 10.1002/14651858.CD003225.pub3
Methods D: crossover C: unclear B: double WD: 6/16 J: 1‐1‐0 DU: ‐/2x8 (no washout)/‐
Participants N: 16/10 D: migraine C: unclear F: 80% A: mean 41 years DU: mean 17 years S: outpatient department, UK
Interventions P: 120 mg C: Placebo
Outcomes R: not reported F: 21 vs. 24 headache days in 56 days (sd not reported) AU: not reported HI: 47 vs. 52 AEs: not reported Dropouts‐AEs: not reported V: (+)
Notes Small study with high dropout rate
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk B ‐ Unclear