Methods | D: crossover C: unclear B: double WD: 1/9 J: 1‐1‐1 DU: ‐/2x2m (no washout)/‐ | |
Participants | N: 9/8 D: 4 migraine with, 5 without aura C: Ad Hoc F: 78% A: 23‐39 years DU: 1‐27 years S: clinical pharmacology department in Granada, Spain | |
Interventions | P: 160 mg C: Placebo | |
Outcomes | R: 4/8 vs. 2/8; 7 preferred propranolol, 1 no preference F: significantly fewer attacks with propranolol AU: not reported HI: not reported AEs: unclear Dropouts‐AEs: 1/9 vs. 0/9 V: + | |
Notes | Extremely small trial with very positive results | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment (selection bias) | Unclear risk | B ‐ Unclear |