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. 2017 Feb 17;2017(2):CD003225. doi: 10.1002/14651858.CD003225.pub3
Methods D: crossover C: unclear B: double WD: 1/9 J: 1‐1‐1 DU: ‐/2x2m (no washout)/‐
Participants N: 9/8 D: 4 migraine with, 5 without aura C: Ad Hoc F: 78% A: 23‐39 years DU: 1‐27 years S: clinical pharmacology department in Granada, Spain
Interventions P: 160 mg C: Placebo
Outcomes R: 4/8 vs. 2/8; 7 preferred propranolol, 1 no preference F: significantly fewer attacks with propranolol AU: not reported HI: not reported AEs: unclear Dropouts‐AEs: 1/9 vs. 0/9 V: +
Notes Extremely small trial with very positive results
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk B ‐ Unclear