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. 2017 Feb 17;2017(2):CD003225. doi: 10.1002/14651858.CD003225.pub3
Methods D: crossover C: unclear B: double WD: 6/25 J: 1‐1‐0 DU: ‐/2x3m (no washout)/‐
Participants N: 25/19 D: 6 migraine with, 13 without aura C: Ad Hoc F: 52% A: 19‐61 years DU: not reported S: unclear, USA
Interventions P: 80 mg C: Placebo
Outcomes R: 1st period: 5/8 vs. 0/11; pooled: 15/19 vs. 2/19 F: not reported AU: not reported HI: not reported AEs: unclear Dropouts‐AEs: 0/25 vs. 0/25 V: +
Notes Small crossover trial with extremely positive results
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk B ‐ Unclear