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. 2017 Feb 20;2017(2):CD002769. doi: 10.1002/14651858.CD002769.pub5

Comparison 2. NIV in overnight ventilation compared to oxygen.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 CFQoL chest symptom score 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.1 Up to 3 months 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
2 CFQoL transitional dyspnoea index 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
2.1 Up to 3 months 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
3 Symptoms of sleep‐disordered breathing 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
3.1 Epworth Sleepiness Scale (up to 3 months) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
3.2 Global PSQI (up to 3 months) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
4 Lung function during sleep 1   Mean Difference (Fixed, 95% CI) Totals not selected
4.1 VI (L/m) while awake (single night) 1   Mean Difference (Fixed, 95% CI) 0.0 [0.0, 0.0]
4.2 VI (L/m) during REM (single night) 1   Mean Difference (Fixed, 95% CI) 0.0 [0.0, 0.0]
4.3 VI (L/m) during NREM (single night) 1   Mean Difference (Fixed, 95% CI) 0.0 [0.0, 0.0]
4.4 VT (L) while awake (single night) 1   Mean Difference (Fixed, 95% CI) 0.0 [0.0, 0.0]
4.5 VT (L) during REM (single night) 1   Mean Difference (Fixed, 95% CI) 0.0 [0.0, 0.0]
4.6 VT (L) during NREM (single night) 1   Mean Difference (Fixed, 95% CI) 0.0 [0.0, 0.0]
5 Respiratory rate (breaths/min) 1   Mean Difference (Fixed, 95% CI) Totals not selected
5.1 RR while awake (single night) 1   Mean Difference (Fixed, 95% CI) 0.0 [0.0, 0.0]
5.2 RR during REM (single night) 1   Mean Difference (Fixed, 95% CI) 0.0 [0.0, 0.0]
5.3 RR during NREM (single night) 1   Mean Difference (Fixed, 95% CI) 0.0 [0.0, 0.0]
6 Lung function while awake 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
6.1 FEV1% predicted (up to 3 months) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
6.2 FVC % predicted (up to 3 months) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
7 Arterial blood gases: pH 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
7.1 Up to 3 months 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
8 Arterial blood gases: PaO2 (mmHg) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
8.1 Up to 3 months 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
9 Arterial blood gases: PaCO2 (mmHg) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
9.1 Up to 3 months 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
10 Arterial blood gases: HCO3 (mmol/L) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
10.1 Up to 3 months 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
11 Arterial blood gases: SaO2 (%) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
11.1 Up to 3 months 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
12 Exercise performance (MSWT) (metres) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
12.1 Up to 3 months 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
13 Total sleep time (min) 2   Mean Difference (IV, Fixed, 95% CI) Totals not selected
13.1 Single night 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
13.2 Up to 3 months 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
14 REM sleep architecture 2   Mean Difference (IV, Fixed, 95% CI) Totals not selected
14.1 REM (single night) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
14.2 REM %TST (single night) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
14.3 REM % TST (up to 3 months) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
15 Sleep latency (min) 3   Mean Difference (IV, Fixed, 95% CI) Subtotals only
15.1 Single night 2 38 Mean Difference (IV, Fixed, 95% CI) 2.93 [‐0.32, 6.19]
15.2 Up to 3 months 1 15 Mean Difference (IV, Fixed, 95% CI) ‐5.0 [‐19.17, 9.17]
16 Nocturnal oxygen saturation (%) 2   Mean Difference (IV, Fixed, 95% CI) Totals not selected
16.1 Mean SpO2 REM (single night) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
16.2 Mean SpO2 NREM (single night) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
16.3 Mean SpO2 for TST (up to 3 months) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
16.4 TST with SpO2 < 90% (up to 3 months) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
17 Nocturnal oxygen saturation (%) 1   Mean Difference (Fixed, 95% CI) Totals not selected
17.1 Percentage TST SpO2>90% 1   Mean Difference (Fixed, 95% CI) 0.0 [0.0, 0.0]
17.2 Percentage REM SpO2>90% 1   Mean Difference (Fixed, 95% CI) 0.0 [0.0, 0.0]
17.3 Percentage NREM SpO2>90% 1   Mean Difference (Fixed, 95% CI) 0.0 [0.0, 0.0]
18 Nocturnal TcCO2 (mmHg 2   Mean Difference (IV, Fixed, 95% CI) Totals not selected
18.1 TcCO2 during REM (single night) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
18.2 TcCO2 during NREM (single night) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
18.3 Mean change PtCO2 (mmHg) (up to 3 months) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
18.4 Mean change PaCO2 (mmHg) (up to 3 months) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
19 Nocturnal TcCO2 (mmHg) 1   Mean Difference (Fixed, 95% CI) Totals not selected
19.1 Mean change TcCO2 NREM to REM (single night) 1   Mean Difference (Fixed, 95% CI) 0.0 [0.0, 0.0]
19.2 Maximum TcCO2 (single night) 1   Mean Difference (Fixed, 95% CI) 0.0 [0.0, 0.0]
20 Nocturnal TcCO2 TST (mmHg) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
20.1 Mean PtCO2 TST (up to 3 months) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
20.2 Maximum PtCO2 TST (up to 3 months) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
21 Hypopneas 1   Relative rate (Fixed, 95% CI) Totals not selected
21.1 Single night 1   Relative rate (Fixed, 95% CI) 0.0 [0.0, 0.0]
22 Mean heart rate (beats/min) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
22.1 Up to 3 months 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
23 Respiratory rate 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
23.1 Up to 3 months 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]