Table 4. Intersection of TF targets and 500 protein-coding genes with the most similar tissue-wide expression profiles.
| TF | Cell line | Number of
targets |
Size of
intersection |
Targets among the most similar 10 genes § |
|---|---|---|---|---|
| EGR1 | K562 | 169 | 12 | None |
| ELF1 | 78 | 5 | None | |
| ELK1 | 112 | 4 | GNL1(8 th) | |
| ETS1 | 267 | 15 | None | |
| GABPA | 513 | 25 | TAF1(1 st) | |
| IRF1 | 457 | 10 | None | |
| YY1 | 1752 | 127 |
MRPL9(2
nd),
BAZ1B(6
th),
ENY2(7
th),
NUB1(8
th),
USP1(9 th), HNRNPR(10 th) |
|
| GM19238 | 1040 | 61 | MED4(1 st), SURF6(3 rd), BAZ1B(6 th) | |
| BATF | 186 | 21 | None | |
| JUND | 44 | 2 | None | |
| NFE2L1 | 58 | 4 | None | |
| RELA | 247 | 13 | HMG20B(9 th) | |
| RXRA | 181 | 3 | None | |
| SP1 | 1595 | 81 | None | |
| TCF12 | 655 | 20 | None | |
| USF1 | 301 | 21 | None | |
| PAX5 | 918 | 86 | IL21R(8 th) | |
| POU2F2 | 532 | 26 | CD86(3 rd) |
§The rank of each target in the list of similar genes in the descending order of Bray-Curtis similarity values is shown in the brackets immediately following the target.