Figure 2.

Tracheal instillation of bleomycin causes decreases in body weight (BW) and body condition score (BCS). (A) Bleomycin instillation causes decreased BW. §, P < 0.0001. (B) Bleomycin instillation causes decreased BCS. §, P < 0.0001. (C) Representative changes in BW and BCS in a bleomycin-treated mouse and a saline control animal. Bleomycin causes an initial drop in BW that is stable until day 5, after which a precipitous drop in BW occurs. Decreases in BCS closely follow the decreases in BW. Saline instillation does not affect BCS, whereas BW slightly increases. (D) Decreases in BW and BCS are strongly correlated with each other.