Comparison 4.

Radioisotopes versus placebo (ITT worst case)

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Pain relief	8		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
1.1 Complete relief (100%)	4	317	Risk Ratio (M‐H, Random, 95% CI)	2.11 [1.32, 3.37]
1.2 Complete/partial relief (50%‐100%)	3	140	Risk Ratio (M‐H, Random, 95% CI)	1.79 [1.16, 2.77]
1.3 Any amount of relief (0%‐100%)	5	319	Risk Ratio (M‐H, Random, 95% CI)	1.42 [0.81, 2.49]
2 Less or equal analgesia consumption	3		Risk Ratio (M‐H, Random, 95% CI)	Totals not selected