Baczyk 2007

Methods	Randomised trial.
Participants	N = 100 prostate and breast cancer patients (60 with prostate carcinoma, 40 with breast carcinoma). Metastatic bone lesions confirmed by 99mTcMDP bone scan. Participants had to have unsatisfactory pain control with NSAID and/or opioids. (50 to 89Sr, 50 to 153SmEDTMP).
Interventions	1. 89Sr at 150 MBq. 2. 153SmEDTMP at 37 MBq/kg of body mass. Follow up: 2 months.
Outcomes	Pain relief with a 0‐10 VAS assessed by the patient two months after treatment. Analgesic consumption assessed as percent dosage reduction of NSAID and opioids assessed two months after treatment. Karnofsky Performance Score assessed two months after treatment. Adverse effects.
Notes	0 patients were lost or withdrawn.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not described.
Allocation concealment (selection bias)	Unclear risk	Not described.
Blinding (performance bias and detection bias) Patients	Unclear risk	Not described.
Blinding (performance bias and detection bias) Study researchers	Unclear risk	Not described.
Blinding (performance bias and detection bias) Outcome assessment	Unclear risk	Not described.
Incomplete outcome data (attrition bias) All outcomes	Low risk	Outcome data are provided for all randomised patients.