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. 2019 Apr 15;13(4):e0007287. doi: 10.1371/journal.pntd.0007287

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© 2019 Wang et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — A, Heatmap of transcriptional variation in expression of immune-related genes (ROS pathways and AMP genes) in DENV-infected mosquitoes. CC_1d_C, carcass 1 day post normal blood meal; CC_1d_I, carcass 1 day post DENV-infected blood meal; CC_2d_C, carcass 2 days post normal blood meal; CC_2d_I, carcass 2 days post DENV-infected blood meal; CC_7d_C, carcass 7 days post normal blood meal; CC_7d_I, carcass 2 days post DENV-infected blood meal; MG_1d_C, midgut 1 day post normal blood meal; MG_1d_I, midgut 1 day post DENV-infected blood meal. B, The regulation of immune pathways in Ae. aegypti in response to viral infection. The left semicircle represents the midguts of mosquitoes infected by DENV 1 d.p.i., the right semicircle represents the carcasses of mosquitoes infected by DENV 2 d.p.i. The color Red represents gene expression increased by DENV infection. The color Blue represents gene expression decreased by DENV infection. The genes with p values less than 0.05 were regarded as differentially expressed.