Fig 3. Chronic mild stress but not ketamine modulates the open field test.

Behavior (8 days post-injection) was automatically scored in EthoVision and parsed into: A, total distance traveled; B, center square entries; C, percent center square time. There was a main effect of stress, indicating modulation of total distance traveled (p < 0.01), as well as percent center square time (p < 0.01), with a trend for center square entries (p = 0.078). Error bars: ± SEM. Two-way ANOVA ** p < 0.01.