Table 2. Factors associated with missing data regarding prescription and completion of latent tuberculosis infection treatment.
953 infected contacts (close and frequent contacts) detected through contact tracing of sputum smear-positive pulmonary tuberculosis cases. Barcelona 2008–2016.
| Prescription and completion of LTBI treatment | ||||||
|---|---|---|---|---|---|---|
| Missing | Non-missing | p-value** | OR | aOR | ||
| [n (%*)] | [n (%*)] | |||||
| Age | <40 years | 82 (14.6) | 478 (85.4) | 0.10 | 1 | |
| ≥40 years | 43 (11.0) | 349 (89.0) | 0.7 (0.5–1.1) | |||
| Sex | Man | 77 (14.1) | 468 (85.9) | 0.29 | 1 | |
| Woman | 48 (11.8) | 360 (88.2) | 0.8 (0.6–1.2) | |||
| Country of origin | Spain | 31 (7.8) | 368 (92.2) | <0.01 | 1 | 1 |
| Foreign-born | 93 (17.3) | 446 (82.7) | 2.5 (1.6–3.8) | 2.3 (1.3–3.8) | ||
| Type of contact | Close | 104 (13.1) | 688 (86.9) | 0.98 | 1 | |
| Frequent | 21 (13.0) | 140 (87.0) | 1.0 (0.6–1.6) | |||
| Setting | Home | 89 (12.1) | 646 (87.9) | 0.09 | 1 | 1 |
| Community | 36 (16.5) | 182 (83.5) | 1.4 (0.9–2.2) | 2.4 (1.4–4.1) | ||
| TST/IGRA conversion | Yes | 3 (3.3) | 89 (96.7) | <0.01 | 1 | 1 |
| No | 122 (14.2) | 739 (85.8) | 4.9 (1.5.15.7) | 5.4 (1.3–22.9) | ||
| Smoking habit | No | 50 (10.4) | 431 (89.6) | 0.21 | 1 | 1 |
| Yes | 33 (13.5) | 211 (86.5) | 1.3 (0.8–2.1) | 1.4 (0.9–2.4) | ||
| DM | No | 85 (11.6) | 647 (88.4) | 0.73 | 1 | |
| Yes | 7 (13.2) | 46 (86.8) | 1.2 (0.5–2.6) | |||
| HIV infection | No | 95 (12.1) | 693 (87.9) | 0.52 | ||
| Yes | 0 (0.0) | 3 (100) | ||||
| Alcohol abuse | No | 78 (11.7) | 590 (88.3) | 0.74 | 1 | |
| Yes | 5 (10.2) | 44 (89.8) | 0.9 (0.3–2.2) | |||
LTBI: latent tuberculosis infection; OR: odds ratio; aOR: odds ratio adjusted by country of origin, setting of contact, TST/IGRA conversion and smoking habit; TST/IGRA conversion: conversion in tuberculin screen test or IGRA seroconversion; DM: diabetes mellitus.
*Percentage over the total without missing values;
**p-value for the univariate analyses.