Table 1. Demographic and routine CSF findings according to disease groups.
IND | NIND | PIND | SC | NND | |
---|---|---|---|---|---|
n | 55 | 89 | 36 | 52 | 21 |
Age, years | 39.3 (16.7–75.1) | 51.7 (21.6–76.3) | 57.5 (26.8–77.0) | 36.8 (22.3–67.9) | 37.6 (22.3–57.4) |
Sex, female, n (%) | 24 (43.6) | 40 (44.9) | 12 (33.3) | 35 (67.3) | 15 (71.4) |
RBC, /μl | 3 (0–4640) | 1 (0–1600) | 1 (0–4800) | 0 (0–250) | 0 (0–3360) |
WBC, /μl | 11 (0–1600) | 1 (0–3) | 1 (0–10) | 1 (0–3) | 0 (0–3) |
CSF total protein, mg/dl | 65 (30–291) | 52 (30–93) | 81 (44–236) | 47 (24–75) | 42 (22–70) |
Qalb | 9.4 (3.5–49.4) | 6.5 (3.3–15.4) | 12.5 (4.8–45.9) | 5.7 (3.0–10.3) | 4.7 (2.3–11.6) |
IgG index | 0.53 (0.39–0.79) | 0.47 (0.39–0.60) | 0.54 (0.40–0.76) | 0.49 (0.38–0.61) | 0.49 (0.36–0.65) |
IgGIF, n (%) | 1 (2)# | 0 | 0 | 0 | 0 |
Data are shown as median (5th– 95th percentile) unless specified otherwise. # % IgGIF according to Reiber (Reiber H. J Neurol Sci. 1994;122:189–203) and Auer & Hegen (Auer M, Hegen H et al. Eur J Neurol. 2016;23:713–721) formulae was 62% and 66%, respectively, in the single patient of the IND group. Clinical diagnosis of this patient was HIV encephalopathy.
Abbreviations: CSF, cerebrospinal fluid; HIV, human immunodeficiency virus; IF, intrathecal fraction; IgG, immunoglobulin G; IND, inflammatory neurological disease; NIND, non-inflammatory neurological disease; NND, no neurological disease; PIND, peripheral inflammatory neurological disease; Qalb, CSF/ serum albumin quotient; RBC, red blood cell; SC, symptomatic control; WBC, white blood cell