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List of interactors putatively not affected by pVHL mutations found in patients presenting a specific a VHL phenotype (left). Phosphorylation sites found to be frequently mutated in both renal manifestations of VHL (collectively including RCC, ccRCC, renal cysts) and pheochromocytoma (right).
| Conserved interactions | Mutated phosphorylation sites | |
|---|---|---|
| Pheochromocytoma | Hemangioblastoma | Renal disease & Pheochromocytoma |
| HSPA4 | TP53 | AURKA |
| AKT1 | ID2 | CSNK2A1 |
| ELAVL1 | CHEK2 | |
| E2F1 | GSK3B | |
| ELOC | NEDD8 | |
