Comparison 9. Topical treatments versus placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Symptom relief ‐ short‐term (≤3 months)	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
1.1 Capsaicin oral rinse	1		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
1.2 Lactoperoxidase oral rinse (Biotene)	1		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
2 Symptom relief ‐ short‐term (≤3 months)	3		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
2.1 Benzydamine hydrochloride oral rinse	1		Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
2.2 Lactoperoxidase oral rinse (Biotene)	1		Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
2.3 Topical urea (10%)	1		Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
3 Symptom relief ‐ long‐term (>3 to ≤6 months)	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
3.1 Capsaicin	1		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
3.2 Lactoperoxidase (Biotene)	1		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]