Baiocchi 2006.
Methods | Randomised clinical trial | |
Participants | Country: Italy Number randomised: 20 Postrandomisation dropouts: 0 (0%) Revised sample size: 20 Average age: 49 years Females: 5 (25%) Primary transplantation: 20 (100%) Retransplantation: 0 (0%) HCV: 8 (40%) HBV: 4 (20%) Alcoholic cirrhosis: 3 (15%) Other causes: 1 (5%) Average follow‐up period in months (for all groups): 3 Additional treatment such as antiviral drugs: lamivudine in HBV patients Important inclusion and exclusion criteria Primary transplantation only: yes Retransplantation only: no HCV only: no HBV only: no Alcoholic cirrhosis only: no Other causes: yes Other important inclusion criteria:
Important exclusion criteria:
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Interventions | Participants were randomly assigned to 2 groups. Group 1: cyclosporine A (n = 10). Further details: cyclosporine A: attain 250 ng/mL. Group 2: tacrolimus (n = 10). Further details: tacrolimus: attain 10 ng/mL. | |
Outcomes | None of the outcomes of interest were reported. | |
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Comment: this information was not available. |
Allocation concealment (selection bias) | Unclear risk | Comment: this information was not available. |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Comment: this information was not available. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Comment: this information was not available. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Comment: there were no postrandomisation dropouts. |
Selective reporting (reporting bias) | High risk | Comment: no published protocol was available; either mortality/graft loss or adverse events, or both were not reported. |
For‐profit bias | Unclear risk | Comment: this information was not available. |
Other bias | Low risk | Comment: no other bias noted. |