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. 2017 Mar 31;2017(3):CD011639. doi: 10.1002/14651858.CD011639.pub2

Baiocchi 2006.

Methods Randomised clinical trial
Participants Country: Italy
Number randomised: 20
Postrandomisation dropouts: 0 (0%)
Revised sample size: 20
Average age: 49 years
Females: 5 (25%)
Primary transplantation: 20 (100%)
Retransplantation: 0 (0%)
HCV: 8 (40%)
HBV: 4 (20%)
Alcoholic cirrhosis: 3 (15%)
Other causes: 1 (5%)
Average follow‐up period in months (for all groups): 3
Additional treatment such as antiviral drugs: lamivudine in HBV patients
Important inclusion and exclusion criteria
Primary transplantation only: yes
Retransplantation only: no
HCV only: no
HBV only: no
Alcoholic cirrhosis only: no
Other causes: yes
Other important inclusion criteria:
  • Elective transplantation


Important exclusion criteria:
  • Multi‐organ transplantation

Interventions Participants were randomly assigned to 2 groups.
 Group 1: cyclosporine A (n = 10).
 Further details: cyclosporine A: attain 250 ng/mL.
 Group 2: tacrolimus (n = 10).
 Further details: tacrolimus: attain 10 ng/mL.
Outcomes None of the outcomes of interest were reported.
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Comment: this information was not available.
Allocation concealment (selection bias) Unclear risk Comment: this information was not available.
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Comment: this information was not available.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Comment: this information was not available.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Comment: there were no postrandomisation dropouts.
Selective reporting (reporting bias) High risk Comment: no published protocol was available; either mortality/graft loss or adverse events, or both were not reported.
For‐profit bias Unclear risk Comment: this information was not available.
Other bias Low risk Comment: no other bias noted.