Study	Reason for exclusion
Abdelmalek 2012	No fixed immunosuppression regimen in either intervention group or control group, or both
Barnes 1997	Not on maintenance immunosuppression
Beckebaum 2004	No fixed immunosuppression regimen in either intervention group or control group, or both
Becker 2008	Not on maintenance immunosuppression
Benitez 2010	Not on maintenance immunosuppression
Berenguer 2006	Randomisation was performed at least 1 year after liver transplantation.
Biancofiore 2004	Not on maintenance immunosuppression
Bilbao 2009	Not on maintenance immunosuppression
Bogetti 2005	Not on maintenance immunosuppression
Boillot 2000	Not on maintenance immunosuppression
Boillot 2001	Not on maintenance immunosuppression
Boillot 2005	Not on maintenance immunosuppression
Boillot 2009	Not on maintenance immunosuppression
Boleslawski 2004	Details of maintenance immunosuppression not available.
Calmus 2010	Not on maintenance immunosuppression
Chen 2005	Comparison of different regimens of same drug
Cicinnati 2007	Randomisation was performed at least 1 year after liver transplantation.
Cillo 2014	Details of maintenance immunosuppression not available.
Cosimi 1987	Not on maintenance immunosuppression
Cosimi 1990	Not on maintenance immunosuppression
Cuervas‐Mons 2015	Not on maintenance immunosuppression
Day 2004	Details of maintenance immunosuppression not available.
De Simone 2009	No fixed immunosuppression regimen in either intervention group or control group, or both
De Simone 2015	Comparison of different regimens of same drug
Duvoux 2015	Randomisation was performed from 6 months to 10 years.
Eason 2003	Not on maintenance immunosuppression
Ericzon 1997	Not on maintenance immunosuppression
Farges 1994	Not on maintenance immunosuppression
Filipponi 2004	Not on maintenance immunosuppression
Firpi 2006	Not a randomised clinical trial
Firpi 2010	Randomisation was performed only after recurrence of hepatitis C infection.
Fischer 2012	No fixed immunosuppression regimen in either intervention group or control group, or both
Fleckenstein 1996	Not on maintenance immunosuppression
Garcia Gonzalez 2005	Not on maintenance immunosuppression
Garcia‐Saenz‐de‐Sicilia 2014	Not on maintenance immunosuppression
Geissler 2016	No fixed immunosuppression regimen in either intervention group or control group, or both
Gerhardt 2009	No fixed immunosuppression regimen in either intervention group or control group, or both
Gonzalez‐Pinto 2005	Although this is a long‐term report of an included study (Loinaz 2001), after the randomisation period was complete, immunosuppression was left to local centre's protocol.
Grant 2012	Not on maintenance immunosuppression
Hardinger 2004	Details of maintenance immunosuppression not available.
Herlenius 2010	No fixed immunosuppression regimen in either intervention group or control group, or both
Hodge 2002	Randomisation was performed between 3 months and 27 months after liver transplantation.
Hytiroglou 1993	Details of maintenance immunosuppression not available.
Junge 2005	Randomisation was performed at least 1 year after liver transplantation.
Kato 2007	Not on maintenance immunosuppression
Keiding 1997	Not on maintenance immunosuppression
Klintmalm 1994	No fixed immunosuppression regimen in either intervention group or control group. or both
Klintmalm 2007	No fixed immunosuppression regimen in either intervention group or control group, or both
Klintmalm 2014	No fixed immunosuppression regimen in either intervention group or control group, or both
Klupp 1998	Not on maintenance immunosuppression
Langrehr 1997	Not on maintenance immunosuppression
Langrehr 1998a	Not on maintenance immunosuppression
Langrehr 1998b	Not on maintenance immunosuppression
Langrehr 2001	Not on maintenance immunosuppression
Langrehr 2002	Not on maintenance immunosuppression
Lerut 2005	Not on maintenance immunosuppression
Lerut 2008	Not on maintenance immunosuppression
Levy 2004	No fixed immunosuppression regimen in either intervention group or control group, or both
Levy 2006	No fixed immunosuppression regimen in either intervention group or control group, or both
Levy 2014	No fixed immunosuppression regimen in either intervention group or control group, or both
Llado 2006	Details of maintenance immunosuppression not available.
Llado 2014	Details of maintenance immunosuppression not available.
Lu 2006a	Details of maintenance immunosuppression not available.
Lupo 2008	Not on maintenance immunosuppression
Margarit 2005	Not on maintenance immunosuppression
McDiarmid 1991	Not on maintenance immunosuppression
McDiarmid 1991a	Not on maintenance immunosuppression
McDiarmid 1993	Includes paediatric population undergoing liver transplants
Moench 2007	Not on maintenance immunosuppression
Mor 1994	Includes paediatric population undergoing liver transplants
Nashan 1996	Not on maintenance immunosuppression
Neuberger 2009	No fixed immunosuppression regimen in either intervention group or control group, or both
Neuhaus 1993	Not a randomised clinical trial
Neuhaus 1994	No fixed immunosuppression regimen in either intervention group or control group, or both
Neuhaus 1997	No fixed immunosuppression regimen in either intervention group or control group, or both
Neuhaus 2000	Not on maintenance immunosuppression
Neuhaus 2002	Not on maintenance immunosuppression
Neumann 2012	Not on maintenance immunosuppression
Nevens 2007	Randomisation was performed after development of renal impairment.
Northup 2006	Details of maintenance immunosuppression not available.
Otero 2009	Not on maintenance immunosuppression
Pageaux 1995	Not on maintenance immunosuppression
Pageaux 2006	Randomisation was performed after development of renal impairment.
Pascher 2015	Details of maintenance immunosuppression not available.
Ramirez 2013	Not on maintenance immunosuppression
Reding 1993	Not on maintenance immunosuppression
Reggiani 2005	Not on maintenance immunosuppression
Reich 2005	Randomisation was performed after development of renal impairment.
Saliba 2016	Details of maintenance immunosuppression not available.
Saliba 2016a	Comparison of different regimens of same drug
Salizzoni 2001	Not clear whether the immunosuppressive regimens were continued beyond the induction phase
Schiano 2006	Not on maintenance immunosuppression
Schmeding 2007	Not on maintenance immunosuppression
Schmeding 2011	No fixed immunosuppression regimen in either intervention group or control group, or both
Shaked 2016	Randomisation was performed at an average of 17 months after liver transplantation.
Shenoy 2007	Randomisation was performed at least 6 months after transplantation only in people with renal dysfunction.
Simone 2008	No fixed immunosuppression regimen in either intervention group or control group, or both
Studenik 2005	Not on maintenance immunosuppression
Takada 2013	Not on maintenance immunosuppression
Teperman 2013	No fixed immunosuppression regimen in either intervention group or control group, or both
Therapondos 2002	Details of maintenance immunosuppression not available.
Timmermann 2002	Details of maintenance immunosuppression not available.
Tisone 1998	Not on maintenance immunosuppression
Trunečka 2015	Not on maintenance immunosuppression
Villamil 2014	Randomisation was performed at least 6 months after liver transplantation.
Washburn 2001	Not on maintenance immunosuppression
Washburn 2008	Not on maintenance immunosuppression
Watson 2007	Randomisation was performed after development of renal impairment.
Wiesner 2001	No fixed immunosuppression regimen in either intervention group or control group, or both
Yoshida 2005	Not on maintenance immunosuppression