| Methods |
Randomised clinical trial |
| Participants |
Country: Italy.
Number randomised: 20.
Post‐randomisation dropouts: not stated.
Revised sample size: 20.
Average age: 42 years.
Females: 5 (25%).
Inclusion criteria: alcoholic for at least 2 years, relatively constant alcohol intake.
Exclusion criteria: not reported. |
| Interventions |
Participants were randomly assigned to two groups.
Group 1 (n = 10): cycloxilic acid 240 mg/day.
Group 2 (n = 10): placebo.
Duration: 1 month treatment |
| Outcomes |
mortality. |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Quote: "Randomized".
Comment: Further details were not available. |
| Allocation concealment (selection bias) |
Unclear risk |
Comment: this information was not available. |
| Blinding of participants and personnel (performance bias)
All outcomes |
Unclear risk |
Quote: "Double‐blind".
Comment: Further details were not available. |
| Blinding of outcome assessment (detection bias)
All outcomes |
Unclear risk |
Quote: "Double‐blind".
Comment: Further details were not available. |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
Comment: there were no post‐randomisation dropouts. |
| Selective reporting (reporting bias) |
High risk |
Comment: adverse events were not reported. |
| For‐profit bias |
Unclear risk |
Comment: this information was not available. |
| Other bias |
Low risk |
Comment: there was no other bias. |
