NCT01005290.
Methods | Randomised open‐label, cross‐over trial |
Participants | Participants will be ≥ 18 years old. Previously untreated systolic pressure result of ≥ 120 < 160 mmHg and diastolic pressure result of ≥ 80 < 100 mmHg |
Interventions | A once‐daily oral dose of the cardiovascular fixed‐dose combination pill (containing 100 mg acetylsalicylic acid, 40 mg simvastatin, and 5 mg ramipril) for 1 week followed by a once‐daily oral dose of the cardiovascular fixed‐dose combination pill (containing 100 mg acetylsalicylic acid, 40 mg simvastatin, and 10 mg ramipril) for 4 weeks Comparator: a once‐daily oral dose of 5 mg ramipril for 1 week followed by a once‐daily oral dose of 10 mg ramipril for 4 weeks |
Outcomes |
Primary outcomes
Secondary outcomes
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Notes |